Rabbit Secondary Antibodies
ABclonal Technology OTC Rabbit mAb
This nuclear gene encodes a mitochondrial matrix enzyme The encoded protein is involved in the urea cycle which functions to detoxify ammonia into urea for excretion Mutations in this enzyme lead to ornithine transcarbamylase deficiency which causes hyperammonemia
ABclonal Technology SMPD3/NSMase2 Rabbit mAb
Predicted to enable phosphatidic acid binding activity phosphatidylserine binding activity and sphingomyelin phosphodiesterase activity Predicted to be involved in positive regulation of exosomal secretion and sphingomyelin metabolic process Predicted to act upstream of or within several processes including animal organ development enzyme linked receptor protein signaling pathway and sphingolipid metabolic process Predicted to be located in Golgi apparatus and plasma membrane Predicted to be active in cytoplasm Biomarker of pulmonary emphysema
Cayman Chemical InTRleukIn18 RabbIt Monclo 1mL
Immunogen: Recombinant human IL-18 • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) IL-18 • Applications: ELISA, ELISA (CAP)
ABclonal Technology NDUFV1 Rabbit mAb
The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V) This gene encodes a 51 kDa subunit of the NADH ubiquinone oxidoreductase complex I a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites Defects in complex I are a common cause of mitochondrial dysfunction a syndrome that occurs in approximately 1 in 10 000 live births Mitochondrial complex I deficiency is linked to myopathies encephalomyopathies and neurodegenerative disorders such as Parkinson s disease and Leigh syndrome Alternative splicing results in multiple transcript variants encoding distinct isoforms
American Research Products Inc Rabbit MatriX Metalloproteinas
Rabbit MatriX Metalloproteinase 13 MMP-13 ELISA Kit from CUSABIO Detection Range 93 75 pg/mL-6000 pg/mL Sensitivity 23 44 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Cayman Chemical p16INK4ACTerm RabbIt Mon 100uL
A selective estrogen receptor covalent antagonist covalently modifies cysteine 530 in the ligand binding domain of wild-type ERa and ERaY537S inhibits expression of the ERa target genes GREB1 and TFF1 in MCF-7 cells overexpressing wild-type ERa (IC50s 2.74 and 1.3 nM respectively) ERaY537S (IC50s 29.38 and 19.4 nM respectively) ERaY537N (IC50s 8.14 and 6.1 nM respectively) ERaY537C (IC50s 12.19 and 9.5 nM respectively) or ERaD538G (IC50s 24.87 and 4 nM respectively) inhibits the growth of MCF-7 cells overexpressing wild-type ERa or ERaY537S (GI50s 1.3 and 8.3 nM respectively) reduces tumor growth in an MCF-7 mouse xenograft model and an ERaY537S/WT ST941 PDX mouse model in a dose-dependent manner
Cayman Chemical IgG3humn RabbIt Monclona 100ug
Immunogen: Human IgG3 • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (-) Human IgG1, IgG2, IgG4, IgM, IgA, IgD, IgE; (-) Cynomolgus monkey, goat, mouse, rat, or rhesus monkey IgG • Applications: ELISA, ICC, IHC
Cayman Chemical ECadhRIn RabbIt MoncLNal 100uL
An analytical reference standard categorized as an arylcyclohexylamine intended for research and forensic applications
ABclonal Technology eIF4EBP1 Rabbit mAb
This gene encodes one member of a family of translation repressor proteins The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs Interaction of this protein with eIF4E inhibits complex assembly and represses translation This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling resulting in its dissociation from eIF4E and activation of mRNA translation
ABclonal Technology TPH-1 Rabbit mAb
This gene encodes a member of the aromatic amino acid hydroxylase family The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin an important hormone and neurotransmitter Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders including schizophrenia somatic anxiety anger-related traits bipolar disorder suicidal behavior addictions and others
ABclonal Technology ABflo 594 Rabbit anti- IgG1
Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response Mouse IgG1 is composed of two heavy chains and two light chains and it is involved in opsonization complement activation and antibody-dependent cell-mediated cytotoxicity It is also involved in the regulation of immune responses including the activation of T cells and the inhibition of B cell activation Mouse IgG1 is widely used in research and diagnostic applications including ELISA Western blotting and immunohistochemistry It is also used in therapeutic applications such as immunotherapy and vaccine development
Cayman Chemical ZAP70NTerm RabbIt Moncl 100uL
A synthetic intermediate has been used in the synthesis of ANANAS and chemotherapeutic conjugates